![]() Types B and C can also cause chronic, lifelong inflammation. viral hepatitis: Hepatitis A, B, C, D, and E can all cause temporary liver inflammation. ![]() Some causes of jaundice due to poor liver function include: Again, the excess is carried into the bloodstream. Any condition that leads to very rapid destruction of red blood cells can create too much bilirubin for even a healthy liver to handle.Bilirubin will then back up into the liver and then into the bloodstream. The gallbladder or its bile ducts can become blocked, preventing excretion of bilirubin into the intestine.The liver itself can be temporarily or permanently damaged, reducing its ability to break down bilirubin (mix it with bile) and move it into the gallbladder.There are three basic ways this process can go wrong: Therefore, it's important to eliminate it from the body as fast as it's produced. Too much bilirubin can be toxic and can cause jaundice. It helps digest food in the intestine and exits the body in the stool. It's then slowly released into the intestine from the gallbladder. The bilirubin leaves the liver via the bile ducts to be stored in the gallbladder directly underneath. The liver also manufactures the other components of bile.īile is a greenish-yellow fluid secreted by the liver that contains cholesterol, bile salts, and waste products such as bilirubin. This releases large amounts of bilirubin. The liver breaks down old, inefficient red blood cells in a process called hemolysis. Normally, large amounts of blood flow each minute through the liver, which may be thought of as the body's chemical processing plant. With time, the liver cells mature and are able to rid the body of excess bilirubin, and the jaundice will disappear. Newborns also temporarily lack sufficient amounts of the enzymes that break down bilirubin. They are just getting rid of these cells around the time of birth, which releases a lot of bilirubin. Instead, jaundice is caused by the fact that fetuses have a different kind of red blood cell than adults. In this case, the yellowing of the skin is not due to liver or gallbladder disease. Jaundice that occurs at the time of birth generally disappears within days, but some babies require phototherapy treatment (special lights that help break down bilirubin). In addition to being caused by problems with the liver, jaundice can also occur among newborns, particularly premature babies. Either the body is producing too much, or it's not getting rid of it fast enough. Jaundice causes yellow skin and eyes because of an excess amount of the bile pigment bilirubin in the fat layer under the skin. Jaundice is a symptom of many medical problems but it is most often associated with conditions of the liver or the gallbladder.
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